The manual-feed sheetfed design is somewhat surprising for a scanner meant primarily for photographic prints.
With the Pandigital scanner, you have the additional choice of scanning directly to a computer hard drive over a USB connection. The key difference is that with the anywhere 2, the only choice is to scan to memory and then move the files to a computer later. Both the anywhere 2 and the PanScn06 let you scan to memory without a computer. The scanner is broadly in the same category as more traditional sheetfed portable scanners like the Editors' Choice Canon imageFormula P-150 Scan-tini ($295 direct, ) that I reviewed earlier this year, but a closer comparison would be to the Apparent Doxie ($129 direct, ), and an even more direct comparison would be to the IRIScan anywhere 2 ($199 direct, ).